WebCPC CPC COOPERATIVE PATENT CLASSIFICATION

C12Q　MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS (immunoassay G01N 33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES

C12Q 1/00 Measuring or testing processes involving enzymes, {nucleic acids} or micro-organisms (measuring or testing apparatus with condition measuring or sensing means, e.g. colony counters C12M 1/34); Compositions therefor; Processes of preparing such compositions

C12Q 1/001 ・{Enzyme electrodes}

C12Q 1/002 ・・{Electrode membranes}

C12Q 1/003 ・・・{Functionalisation}

C12Q 1/004 ・・{mediator-assisted}

C12Q 1/005 ・・{involving specific analytes or enzymes (including groups of enzymes, e.g. oxydases; C12Q 1/004 takes precedence)}

C12Q 1/006 ・・・{for glucose}

C12Q 1/007 ・{involving isoenzyme profiles (for detection of an individual isoenzyme C12Q 1/25 to C12Q 1/66)}

C12Q 1/008 ・{for determining co-enzymes or co-factors, e.g. NAD, ATP}

C12Q 1/02 ・involving viable micro-organisms

C12Q 1/025 ・・{for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics (antimicrobial activity C12Q 1/18)}

C12Q 1/04 ・・Determining presence or kind of micro-organism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor {(C12Q 1/6897 takes precedence)}

C12Q 1/045 ・・・{Culture media therefor}

C12Q 1/06 ・・・Quantitative determination

C12Q 1/08 ・・・・using multifield media

C12Q 1/10 ・・・Enterobacteria

C12Q 1/12 ・・・Nitrate to nitrite reducing bacteria

C12Q 1/14 ・・・Streptococcus; Staphylococcus

C12Q 1/16 ・・・using radioactive material

C12Q 1/18 ・・Testing for antimicrobial activity of a material

C12Q 1/20 ・・・using multifield media

C12Q 1/22 ・・Testing for sterility conditions

C12Q 1/24 ・・Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact micro-organisms

C12Q 1/25 ・involving enzymes not classifiable in groups C12Q 1/26{to C12Q 1/66}

C12Q 1/26 ・involving oxidoreductase

C12Q 1/28 ・・involving peroxidase

C12Q 1/30 ・・involving catalase

C12Q 1/32 ・・involving dehydrogenase

C12Q 1/34 ・involving hydrolase

C12Q 1/37 ・・involving peptidase or proteinase

C12Q 1/40 ・・involving amylase

C12Q 1/42 ・・involving phosphatase

C12Q 1/44 ・・involving esterase

C12Q 1/46 ・・・involving cholinesterase

C12Q 1/48 ・involving transferase

C12Q 1/485 ・・{involving kinase}

C12Q 1/50 ・・involving creatine phosphokinase

C12Q 1/52 ・・involving transaminase

C12Q 1/527 ・involving lyase

C12Q 1/533 ・involving isomerase

C12Q 1/54 ・involving glucose or galactose

C12Q 1/56 ・involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen

C12Q 1/58 ・involving urea or urease

C12Q 1/60 ・involving cholesterol

C12Q 1/61 ・involving triglycerides

C12Q 1/62 ・involving uric acid

C12Q 1/64 ・Geomicrobiological testing, e.g. for petroleum

C12Q 1/66 ・involving luciferase

C12Q 1/68 ・involving nucleic acids

C12Q 1/6802 ・・{General aspects (not used, see subgroups)}

C12Q 1/6804 ・・・{Nucleic acid analysis utilising immunogens}

C12Q 1/6806 ・・・{Preparing nucleic acids for analysis, e.g. for PCR assay (C12Q 1/6804 takes precedence)}

C12Q 1/6809 ・・・{Sequence identification involving differential detection}

C12Q 1/6811 ・・・{Selection methods for production or design of target specific oligonucleotide or binding molecules}

C12Q 1/6813 ・・{Hybridisation assays}

C12Q 1/6816 ・・・{characterised by the means of detection (C12Q 1/6804 takes precedence)}

C12Q 1/6818 ・・・・{involving interaction of at least two labels, e.g. resonant energy transfer}

C12Q 1/682 ・・・・{Signal amplification}

C12Q 1/6823 ・・・・{Release of bound marker}

C12Q 1/6825 ・・・・{Nucleic acid detection involving sensors}

C12Q 1/6827 ・・・{for mutation or polymorphism detection}

C12Q 1/683 ・・・・{involving restriction enzymes, e.g. RFLP}

C12Q 1/6832 ・・・{Enhancement of hybridisation reaction}

C12Q 1/6834 ・・・{Nucleic acid analysis involving immobilisation; Immobilisation characterised by the carrier or coupling agent}

C12Q 1/6837 ・・・・{characterised by the use of probe arrays or probe chips (C12Q 1/6874 takes precedence)}

C12Q 1/6839 ・・・{Triple helix formation in hybridisation assays}

C12Q 1/6841 ・・・{"In-situ" hybridisation}

C12Q 1/6844 ・・{Nucleic acid amplification reactions}

C12Q 1/6846 ・・・{Common amplification features}

C12Q 1/6848 ・・・・{preventing contamination}

C12Q 1/6851 ・・・・{Quantitative amplification}

C12Q 1/6853 ・・・・{using modified primers or templates}

C12Q 1/6855 ・・・・・{Ligating adaptors}

C12Q 1/6858 ・・・・{Allele specific amplification}

C12Q 1/686 ・・・{Polymerase Chain Reaction (PCR)}

C12Q 1/6862 ・・・{Ligase Chain Reaction (LCR)}

C12Q 1/6865 ・・・{Promoter based amplification, e.g. NASBA, 3SR, TAS}

C12Q 1/6867 ・・・{Replicase based amplifications, e.g. Q-beta replicase}

C12Q 1/6869 ・・{Methods for sequencing}

C12Q 1/6872 ・・・{involving mass spectrometry}

C12Q 1/6874 ・・・{involving nucleic acid arrays, e.g. Sequencing By Hybridisation (SBH)}

C12Q 1/6876 ・・{Hybridisation probes}

C12Q 1/6879 ・・・{for sex determination}

C12Q 1/6881 ・・・{for tissue and cell typing, e.g. HLA probes}

C12Q 1/6883 ・・・{for diseases caused by alterations of genetic material}

C12Q 1/6886 ・・・・{for cancer}

C12Q 1/6888 ・・・{for detection or identification of organisms}

C12Q 1/689 ・・・・{for bacteria}

C12Q 1/6893 ・・・・{for protozoa}

C12Q 1/6895 ・・・・{for plants, fungi, or algae}

C12Q 1/6897 ・・{involving reporter genes operably linked to promoters}

C12Q 1/70 ・involving virus or bacteriphage

C12Q 1/701 ・・{Specific hybridization probes}

C12Q 1/702 ・・・{for retroviruses}

C12Q 1/703 ・・・・{Viruses associated with AIDS}

C12Q 1/705 ・・・{for herpetoviridae, e.g. herpes simplex, varicella zoster}

C12Q 1/706 ・・・{for hepatitis}

C12Q 1/707 ・・・・{non-A, non-B Hepatitis, excluding hepatitis D}

C12Q 1/708 ・・・{for papilloma}

C12Q 3/00 Condition responsive control processes (apparatus therefor C12M 1/36; controlling or regulating in general G05)

C12Q 2304/00 Chemical means of detecting micro-organisms (hydrolase substrates C12Q 2334/00, peptidase substrates C12Q 2337/00)

C12Q 2304/10 ・DNA staining

C12Q 2304/12 ・・Ethidium

C12Q 2304/13 ・・Propidium

C12Q 2304/16 ・・Acridine orange

C12Q 2304/18 ・・Thionin-type dyes, e.g. Azure, Toluidine Blue

C12Q 2304/20 ・Redox indicators

C12Q 2304/22 ・・Resazurin; Resorufin

C12Q 2304/24 ・・Tetrazolium; Formazan

C12Q 2304/26 ・・Quinone; Quinol

C12Q 2304/40 ・Detection of gases

C12Q 2304/44 ・・Oxygen

C12Q 2304/46 ・・Carbon dioxide

C12Q 2304/48 ・・Ammonia or volatile amines

C12Q 2304/60 ・Chemiluminescent detection using ATP-luciferin-luciferase system

C12Q 2304/80 ・Electrochemical detection via electrodes in contact with culture medium

C12Q 2326/00 Chromogens for determinations of oxidoreductase enzymes

C12Q 2326/10 ・Benzidines

C12Q 2326/12 ・・3,3`,5,5`-Tetramethylbenzidine, i.e. TMB

C12Q 2326/14 ・・Ortho-Tolidine, i.e. 3,3`-dimethyl-(1,1`-biphenyl-4,4`-diamine)

C12Q 2326/20 ・Ortho-Phenylenediamine

C12Q 2326/30 ・2,2`-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid), i.e. ABTS

C12Q 2326/32 ・3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate, i.e. MBTH

C12Q 2326/40 ・Triphenylmethane dye chromogens, e.g. fluorescein derivatives

C12Q 2326/50 ・Phenols; Naphthols; Catechols

C12Q 2326/90 ・Developer

C12Q 2326/92 ・・Nitro blue tetrazolium chloride, i.e. NBT

C12Q 2326/96 ・・4-Amino-antipyrine

C12Q 2334/00 O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases

C12Q 2334/10 ・p-Nitrophenol derivatives

C12Q 2334/20 ・Coumarin derivatives

C12Q 2334/22 ・・4-Methylumbelliferyl, i.e. beta-methylumbelliferone, 4MU

C12Q 2334/30 ・Naphthol derivatives, e.g. alpha-naphthyl-esters, i.e. alpha-NE, beta-naphthyl-esters, i.e. beta-NE

C12Q 2334/40 ・Triphenylmethane dye chromogens, e.g. fluorescein derivatives

C12Q 2334/50 ・Indoles

C12Q 2334/52 ・・5-Bromo-4-chloro-3-indolyl, i.e. BCI

C12Q 2334/70 ・the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red

C12Q 2337/00 N-linked chromogens for determinations of peptidases and proteinases

C12Q 2337/10 ・Anilides

C12Q 2337/12 ・・Para-Nitroanilides p-NA

C12Q 2337/20 ・Coumarin derivatives

C12Q 2337/22 ・・7-Amino-4-methylcoumarin, i.e. AMC, MCA

C12Q 2337/24 ・・7-Amino-4-trifluoromethylcoumarin, i.e. AFC

C12Q 2337/30 ・Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA

C12Q 2337/40 ・Rhodamine derivatives

C12Q 2337/50 ・Indoles

C12Q 2337/52 ・・5-Bromo-4-chloro-3-indolyl, i.e. BCI

C12Q 2500/00 Analytical methods involving nucleic acids (not used)

C12Q 2520/00 Reactions involving nucleic acids (not used)

C12Q 2521/00 Reaction characterised by the enzymatic activity (not used)

C12Q 2521/10 ・Nucleotidyl transfering (not used)

C12Q 2521/101 ・・DNA polymerase

C12Q 2521/107 ・・RNA dependent DNA polymerase, (i.e. reverse transcriptase)

C12Q 2521/113 ・・Telomerase

C12Q 2521/119 ・・RNA polymerase

C12Q 2521/125 ・・Methyl transferase, i.e. methylase

C12Q 2521/131 ・・Terminal transferase

C12Q 2521/30 ・Phosphoric diester hydrolysing, i.e. nuclease (Not used)

C12Q 2521/301 ・・Endonuclease

C12Q 2521/307 ・・Single strand endonuclease

C12Q 2521/313 ・・Type II endonucleases, i.e. cutting outside recognition site

C12Q 2521/319 ・・Exonuclease

C12Q 2521/325 ・・Single stranded exonuclease

C12Q 2521/327 ・・RNAse, e.g. RNAseH

C12Q 2521/331 ・・Methylation site specific nuclease

C12Q 2521/337 ・・Ribozyme

C12Q 2521/343 ・・Abzyme

C12Q 2521/345 ・・DNAzyme

C12Q 2521/50 ・Other enzymatic activities (Not used)

C12Q 2521/501 ・・Ligase

C12Q 2521/507 ・・Recombinase

C12Q 2521/513 ・・Winding/unwinding enzyme, e.g. helicase

C12Q 2521/514 ・・Mismatch repair protein

C12Q 2521/519 ・・Topoisomerase

C12Q 2521/525 ・・Phosphatase (Not used with code C12Q 2565/301)

C12Q 2521/531 ・・Glycosylase

C12Q 2521/537 ・・Protease

C12Q 2521/539 ・・Deaminase

C12Q 2521/543 ・・Immobilised enzyme(s)

C12Q 2522/00 Reaction characterised by the use of non-enzymatic proteins (not used)

C12Q 2522/10 ・Nucleic acid binding proteins (not used)

C12Q 2522/101 ・・Single or double stranded nucleic acid binding proteins

C12Q 2523/00 Reactions characterised by treatment of reaction samples (not used)

C12Q 2523/10 ・Characterised by chemical treatment (Not used)

C12Q 2523/101 ・・Crosslinking agents, e.g. psoralen

C12Q 2523/107 ・・Chemical cleaving agents

C12Q 2523/109 ・・chemical ligation between nucleic acids

C12Q 2523/113 ・・Denaturating agents

C12Q 2523/115 ・・oxidising agents

C12Q 2523/119 ・・Renaturing agents

C12Q 2523/125 ・・Bisulfite(s)

C12Q 2523/30 ・Characterised by physical treatment (Not used)

C12Q 2523/301 ・・Sonication

C12Q 2523/303 ・・Applying a physical force on a nucleic acid

C12Q 2523/305 ・・Denaturation or renaturation by physical action

C12Q 2523/307 ・・Denaturation or renaturation by electric current/voltage

C12Q 2523/308 ・・Adsorption or desorption

C12Q 2523/31 ・・Electrostatic interactions, e.g. use of cationic polymers in hybridisation reactions

C12Q 2523/313 ・・Irradiation, e.g. UV irradiation

C12Q 2523/319 ・・Photocleavage, photolysis, photoactivation

C12Q 2523/32 ・・Centrifugation

C12Q 2525/00 Reactions involving modified oligonucleotides, nucleic acids, or nucleotides

C12Q 2525/10 ・Modifications characterised by

C12Q 2525/101 ・・incorporating non-naturally occurring nucleotides, e.g. inosine

C12Q 2525/107 ・・incorporating a peptide nucleic acid

C12Q 2525/113 ・・incorporating modified backbone

C12Q 2525/117 ・・incorporating modified base

C12Q 2525/119 ・・incorporating abasic sites

C12Q 2525/121 ・・incorporating both deoxyribonucleotides and ribonucleotides

C12Q 2525/125 ・・incorporating agents resulting in resistance to degradation

C12Q 2525/131 ・・incorporating a restriction site

C12Q 2525/137 ・・incorporating/modifying moieties to eliminate restriction sites

C12Q 2525/143 ・・incorporating a promoter sequence (Not used with code C12Q 2531/143)

C12Q 2525/149 ・・incorporating a coding sequence

C12Q 2525/15 ・・incorporating a consensus or conserved sequence

C12Q 2525/151 ・・repeat or repeated sequences, e.g. VNTR, microsatellite, concatemer

C12Q 2525/155 ・・incorporating/generating a new priming site

C12Q 2525/161 ・・incorporating target specific and non-target specific sites

C12Q 2525/173 ・・incorporating a polynucleotide run, e.g. polyAs, polyTs

C12Q 2525/179 ・・incorporating arbitrary or random nucleotide sequences

C12Q 2525/185 ・・incorporating base(s) where the precise position of the base(s) in the nucleic acid string is important (Not to be used for 3'-end base)

C12Q 2525/186 ・・incorporating a non-extendable or blocking moiety (not used with C12Q 2535/101)

C12Q 2525/191 ・・incorporating an adaptor

C12Q 2525/197 ・・incorporating a spacer/coupling moiety

C12Q 2525/203 ・・incorporating a composite nucleic acid containing a polypeptide sequence other than PNA

C12Q 2525/204 ・・specific length of the oligonucleotides

C12Q 2525/205 ・・Aptamer

C12Q 2525/207 ・・siRNA, miRNA

C12Q 2525/30 ・Oligonucleotides characterised by their secondary structure

C12Q 2525/301 ・・Hairpin oligonucleotides

C12Q 2525/307 ・・Circular oligonucleotides

C12Q 2525/313 ・・Branched oligonucleotides

C12Q 2527/00 Reactions demanding special reaction conditions (not used)

C12Q 2527/10 ・Reaction conditions characterised by (metal/ion C12Q 2563/137)(not used)

C12Q 2527/101 ・・Temperature

C12Q 2527/107 ・・Temperature of melting, i.e. Tm

C12Q 2527/109 ・・Pressure

C12Q 2527/113 ・・Time

C12Q 2527/119 ・・pH

C12Q 2527/125 ・・Specific component of sample, medium or buffer (for metal/ion use C12Q 2563/137)

C12Q 2527/127 ・・the enzyme inhibitor or activator used N0611]

C12Q 2527/137 ・・Concentration of a component of medium

C12Q 2527/143 ・・Concentration of primer/probe

C12Q 2527/146 ・・Concentration of target/template

C12Q 2527/149 ・・Concentration of an enzyme

C12Q 2527/15 ・・Gradients

C12Q 2527/153 ・・Viscosity

C12Q 2527/156 ・・Permeability

C12Q 2531/00 Reactions of nucleic acids characterised by

C12Q 2531/10 ・the purpose being amplify/increase the copy number of target nucleic acid (Not used)

C12Q 2531/101 ・・Linear amplification, i.e. non exponential

C12Q 2531/107 ・・Asymmetric PCR

C12Q 2531/113 ・・PCR

C12Q 2531/119 ・・Strand displacement amplification (SDA)

C12Q 2531/125 ・・Rolling circle

C12Q 2531/131 ・・Inverse PCR

C12Q 2531/137 ・・Ligase Chain Reaction (LCR)

C12Q 2531/143 ・・Promoter based amplification, e.g. NASBA, 3SR, TAS

C12Q 2531/149 ・・Replicase based amplification, e.g. Q beta replicase C12Q 2533/00

C12Q 2533/10 ・the purpose being to increase the length of an oligonucleotide strand (ligase detection reaction, LDR C12Q 2561/125)

C12Q 2533/101 ・・Primer extension (see also codes M535/125, M565/537)

C12Q 2533/107 ・・Probe/oligonucleotide ligation (Not used with code M21Q 531/137, M21Q 561/125) C12Q 2535/00

C12Q 2535/10 ・the purpose being to determine the identity or sequence oligonucleotides characterised by (Not used)

C12Q 2535/101 ・・Sanger sequencing method, i.e. oligonucleotide sequencing using primer elongation and dideoxynucleotides as chain terminators

C12Q 2535/107 ・・Maxam and Gilbert method, i.e. sequential release and detection of nucleotides

C12Q 2535/113 ・・Cycle sequencing

C12Q 2535/119 ・・Double strand sequencing

C12Q 2535/122 ・・Massive parallel sequencing

C12Q 2535/125 ・・Allele specific primer extension

C12Q 2535/131 ・・Allele specific probes

C12Q 2535/137 ・・Amplification Refractory Mutation System (ARMS)

C12Q 2535/138 ・・Amplified fragment length polymorphism (AFLP)

C12Q 2535/139 ・・Random amplification polymorphism detection (RAPD) (not to be used with C12Q 2525/179) C12Q 2537/00

C12Q 2537/10 ・the purpose or use of

C12Q 2537/101 ・・Homogeneous assay format, e.g. one pot reaction

C12Q 2537/107 ・・Homoduplex formation

C12Q 2537/113 ・・Heteroduplex formation

C12Q 2537/119 ・・Triple helix formation

C12Q 2537/125 ・・Sandwich assay format

C12Q 2537/137 ・・a displacement step (Not used with code (C12Q 2531/119))

C12Q 2537/1373 ・・・Displacement by a nucleic acid

C12Q 2537/1376 ・・・Displacement by an enzyme

C12Q 2537/143 ・・Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis

C12Q 2537/149 ・・Sequential reactions (Not used with reactions implicitly known to be sequential, e.g. amplification reactions)

C12Q 2537/155 ・・Cyclic reactions (Not used with codes C12Q 2531/101 to C12Q 2531/149)

C12Q 2537/157 ・・A reaction step characterised by the number of molecules incorporated or released

C12Q 2537/159 ・・Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions

C12Q 2537/16 ・・Assays for determining copy number or wherein the copy number is of special importance

C12Q 2537/161 ・・A competitive reaction step (Not used with code C12Q 2545/107)

C12Q 2537/162 ・・Helper probe

C12Q 2537/163 ・・blocking probe (not used in combination with C12Q 2527/127 or C12Q 2525/186)

C12Q 2537/164 ・・Methylation detection other then bisulfite or methylation sensitive restriction endonucleases

C12Q 2537/165 ・・Mathematical modelling, e.g. logarithm, ratio C12Q 2539/00

C12Q 2539/10 ・The purpose being sequence identification by analysis of gene expression or genome comparison characterised by

C12Q 2539/101 ・・Subtraction analysis

C12Q 2539/103 ・・Serial analysis of gene expression (SAGE)

C12Q 2539/105 ・・Involving introns, exons, or splice junctions

C12Q 2539/107 ・・Representational Difference Analysis (RDA)

C12Q 2539/113 ・・Differential Display Analysis (DDA)

C12Q 2539/115 ・・Comparative genomic hybridisation (CGH) C12Q 2541/00

C12Q 2541/10 ・the purpose being the selection/design of target specific nucleic acid binding sequences (not used)

C12Q 2541/101 ・・Selex C12Q 2543/00

C12Q 2543/10 ・the purpose being "in situ" analysis

C12Q 2543/101 ・・in situ amplification C12Q 2545/00

C12Q 2545/10 ・the purpose being quantitative analysis (Not used)

C12Q 2545/101 ・・with an internal standard/control

C12Q 2545/107 ・・with a competitive internal standard/control

C12Q 2545/113 ・・with an external standard/control, i.e. control reaction is separated from the test/target reaction

C12Q 2545/114 ・・involving a quantitation step (not to be used with C12Q 2545/101, C12Q 2545/107, C12Q 2545/113) C12Q 2547/00

C12Q 2547/10 ・the purpose being preventing contamination (Not used)

C12Q 2547/101 ・・by confinement to a single tube/container

C12Q 2547/107 ・・Use of permeable barriers, e.g. waxes C12Q 2549/00

C12Q 2549/10 ・the purpose being that of reducing false positive/negative signals (Not used)

C12Q 2549/101 ・・Hot start

C12Q 2549/107 ・・Cold start

C12Q 2549/113 ・・using nested probes

C12Q 2549/119 ・・using nested primers

C12Q 2549/125 ・・using sterilising/blocking agents, e.g. albumin

C12Q 2549/126 ・・using oligonucleotides as clamps (not to be used with C12Q 2525/107)

C12Q 2560/00 Nucleic acid detection (not used)

C12Q 2561/00 Nucleic acid detection characterised by assay method (not used)

C12Q 2561/10 ・Characterised by assay method (Not used)

C12Q 2561/101 ・・Taqman

C12Q 2561/107 ・・Enzyme complementation

C12Q 2561/108 ・・Hybridisation protection assay (HPA)

C12Q 2561/109 ・・Invader technology

C12Q 2561/113 ・・Real time assay

C12Q 2561/119 ・・Fluorescence polarisation

C12Q 2561/12 ・・Fluorescence lifetime measurement

C12Q 2561/125 ・・Ligase Detection Reaction (LDR)

C12Q 2561/127 ・・Protein truncation assay

C12Q 2563/00 Nucleic acid detection characterised by the use of (not used)

C12Q 2563/101 ・radioactivity, e.g. radioactive labels

C12Q 2563/103 ・luminescence

C12Q 2563/107 ・fluorescence

C12Q 2563/113 ・the label being electroactive, e.g. redox labels

C12Q 2563/116 ・electrical properties of nucleic acids, e.g. impedance, conductivity or resistance

C12Q 2563/119 ・the label being proteinic

C12Q 2563/125 ・the label being enzymatic, i.e. proteins, and non proteins, such as nucleic acid with enzymatic activity

C12Q 2563/131 ・the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin

C12Q 2563/137 ・Metal/ion, e.g metal label

C12Q 2563/143 ・Magnetism, e.g. magnetic label

C12Q 2563/149 ・Particles, e.g. beads

C12Q 2563/155 ・Particles of a defined size, e.g. nanoparticles

C12Q 2563/157 ・Nanotubes or nanorods

C12Q 2563/159 ・Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components

C12Q 2563/161 ・Vesicles, e.g. liposome

C12Q 2563/167 ・Mass label

C12Q 2563/173 ・staining/intercalating agent, e.g. ethidium bromide

C12Q 2563/179 ・the label being a nucleic acid

C12Q 2563/185 ・Nucleic acid dedicated to use as a hidden marker/bar code, e.g. inclusion of nucleic acids to mark art objects or animals

C12Q 2565/00 Nucleic acid analysis characterised by mode or means of detection

C12Q 2565/10 ・Detection mode being characterised by (Not used)

C12Q 2565/101 ・・Interaction between at least two labels

C12Q 2565/1015 ・・・labels being on the same oligonucleotide

C12Q 2565/102 ・・Multiple non-interacting labels

C12Q 2565/1025 ・・・labels being on the same oligonucleotide

C12Q 2565/107 ・・Alteration in the property of hybridised versus free label oligonucleotides

C12Q 2565/113 ・・based on agglutination/precipitation

C12Q 2565/119 ・・based on extraction of label to an organic phase, i.e. partitioning of label between different organic phases

C12Q 2565/125 ・・Electrophoretic separation

C12Q 2565/131 ・・Single/double strand conformational analysis, i.e. SSCP/DSCP

C12Q 2565/133 ・・conformational analysis

C12Q 2565/137 ・・Chromatographic separation

C12Q 2565/20 ・Detection means characterised by being a gene reporter based analysis (Not used)

C12Q 2565/201 ・・Two hybrid system

C12Q 2565/207 ・・Three hybrid system

C12Q 2565/30 ・Detection characterised by liberation/release of label (Not used)

C12Q 2565/301 ・・Pyrophosphate (PPi)

C12Q 2565/40 ・Detection characterised by signal amplification of label (not used)

C12Q 2565/401 ・・Signal amplification by chemical polymerisation

C12Q 2565/50 ・Detection characterised by immobilisation to a surface

C12Q 2565/501 ・・being on/an array of oligonucleotides

C12Q 2565/507 ・・characterised by the density of the capture oligonucleotide

C12Q 2565/513 ・・characterised by the pattern of the arrayed oligonucleotides

C12Q 2565/514 ・・characterised by the use of the arrayed oligonucleotides as identifier tags, e.g. universal addressable array, anti-tag or tag complement array

C12Q 2565/515 ・・characterised by the interaction between or sequential use of two or more arrays

C12Q 2565/518 ・・characterised by the immobilisation of the nucleic acid sample or target

C12Q 2565/519 ・・characteirsed by the capture moiety being a single stranded oligonucleotide

C12Q 2565/525 ・・characterised by the capture oligonucleotide being double stranded

C12Q 2565/531 ・・characterised by the capture moiety being a protein for target oligonucleotides

C12Q 2565/537 ・・characterised by the capture oligonucleotide acting as a primer

C12Q 2565/543 ・・characterised by the use of two or more capture oligonucleotide primers in concert, e.g. bridge amplification (Not used with code C12Q 2537/149)

C12Q 2565/549 ・・characterised by the capture oligonucleotide being a reporter labelled capture oligonucleotide

C12Q 2565/60 ・Detection means characterised by use of a special device (Not used)

C12Q 2565/601 ・・being a microscope, e.g. atomic force microscopy (AFM)

C12Q 2565/607 ・・being a sensor, e.g. electrode

C12Q 2565/619 ・・being a video camera

C12Q 2565/625 ・・being a nucleic acid test strip device, e.g. dipsticks, strips,tapes, CD plates

C12Q 2565/626 ・・being a flow cytometer

C12Q 2565/627 ・・being a mass spectrometer (not to be used with C12Q 2563/167)

C12Q 2565/628 ・・being a surface plasmon resonance spectrometer

C12Q 2565/629 ・・being a microfluidic device

C12Q 2565/631 ・・being a biochannel or pore

C12Q 2565/632 ・・being a surface enhanced, e.g. resonance, Raman spectrometer

C12Q 2565/633 ・・NMR

C12Q 2565/634 ・・being an acoustic wave sensor

C12Q 2600/00 Oligonucleotides characterized by their use (not used, see subgroups)

C12Q 2600/106 ・Pharmacogenomics , i.e. genetic variability in individual responses to drugs and drug metabolism

C12Q 2600/112 ・Disease subtyping, staging or classification

C12Q 2600/118 ・Prognosis of disease development

C12Q 2600/124 ・Animal traits, i.e. production traits, including athletic performance or the like

C12Q 2600/13 ・Plant traits

C12Q 2600/136 ・Screening for pharmacological compounds

C12Q 2600/142 ・Toxicological screening, e.g. expression profiles which identify toxicity

C12Q 2600/148 ・Screening for cosmetic compounds

C12Q 2600/154 ・Methylation markers

C12Q 2600/156 ・Polymorphic or mutational markers

C12Q 2600/158 ・Expression markers

C12Q 2600/16 ・Primer sets for multiplex assays

C12Q 2600/166 ・Oligonucleotides used as internal standards, controls or normalisation probes

C12Q 2600/172 ・Haplotypes

C12Q 2600/178 ・miRNA, siRNA or ncRNA