WebCPC CPC COOPERATIVE PATENT CLASSIFICATION

C07K　PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D 519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G 69/00; macromolecular products derived from proteins C08H 1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N 15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N 33/00)

C07K 1/00 General methods for the preparation of peptides {i.e. processes for the organic chemical preparation of peptides or proteins of any length}

C07K 1/003 ・{by transforming the C-terminal amino acid to amides}

C07K 1/006 ・{of peptides containing derivatised side chain amino acids}

C07K 1/02 ・in solution {(C07K 1/003, C07K 1/006 take precedence)}

C07K 1/023 ・・{using racemisation inhibiting agents}

C07K 1/026 ・・{by fragment condensation in solution}

C07K 1/04 ・on carriers {(C07K 1/003, C07K 1/006 take precedence)}

C07K 1/042 ・・{characterised by the nature of the carrier}

C07K 1/045 ・・{using devices to improve synthesis, e.g. reactors, special vessels}

C07K 1/047 ・・{Simultaneous synthesis of different peptide species; Peptide libraries}

C07K 1/06 ・using protecting groups or activating agents {(C07K 1/003, C07K 1/006 take precedence)}

C07K 1/061 ・・{using protecting groups}

C07K 1/062 ・・・{for alpha- or omega-carboxy functions}

C07K 1/063 ・・・{for alpha-amino functions}

C07K 1/064 ・・・{for omega-amino or -guanidino functions}

C07K 1/065 ・・・{for hydroxy functions, not being part of carboxy functions}

C07K 1/066 ・・・{for omega-amido functions}

C07K 1/067 ・・・{for sulfur-containing functions}

C07K 1/068 ・・・{for heterocyclic side chains}

C07K 1/08 ・・using activating agents {(C07K 1/003, C07K 1/006 take precedence)}

C07K 1/082 ・・・{containing phosphorus}

C07K 1/084 ・・・{containing nitrogen}

C07K 1/086 ・・・{containing sulfur}

C07K 1/088 ・・・{containing other elements, e.g. B, Si, As}

C07K 1/10 ・using coupling agents {(C07K 1/006 takes precedence)}

C07K 1/107 ・by chemical modification of precursor peptides

C07K 1/1072 ・・{by covalent attachment of residues or functional groups}

C07K 1/1075 ・・・{by covalent attachment of amino acids or peptide residues}

C07K 1/1077 ・・・{by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids}

C07K 1/113 ・・without change of the primary structure

C07K 1/1133 ・・・{by redox-reactions involving cystein/cystin side chains}

C07K 1/1136 ・・・{by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents}

C07K 1/12 ・by hydrolysis {i.e. solvolysis in general}

C07K 1/122 ・・{Hydrolysis with acids different from HF}

C07K 1/124 ・・{Hydrazinolysis}

C07K 1/126 ・・{Aminolysis}

C07K 1/128 ・・{sequencing}

C07K 1/13 ・Labelling of peptides

C07K 1/14 ・Extraction; Separation; Purification

C07K 1/145 ・・{by extraction or solubilisation}

C07K 1/16 ・・by chromatography

C07K 1/165 ・・・{mixed-mode chromatography}

C07K 1/18 ・・・Ion-exchange chromatography

C07K 1/20 ・・・Partition-, reverse-phase or hydrophobic interaction chromatography

C07K 1/22 ・・・Affinity chromatography or related techniques based upon selective absorption processes

C07K 1/24 ・・by electrochemical means

C07K 1/26 ・・・Electrophoresis

C07K 1/28 ・・・・Isoelectric focusing

C07K 1/285 ・・・・・{multi dimensional electrophoresis}

C07K 1/30 ・・by precipitation

C07K 1/303 ・・・{by salting out}

C07K 1/306 ・・・{by crystallization}

C07K 1/32 ・・・as complexes

C07K 1/34 ・・by filtration, ultrafiltration or reverse osmosis

C07K 1/36 ・・by a combination of two or more processes of different types

C07K 2/00 Peptides of undefined number of amino acids; Derivatives thereof

C07K 4/00 Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof

C07K 4/02 ・from viruses

C07K 4/04 ・from bacteria

C07K 4/06 ・from fungi

C07K 4/08 ・from algae; from lichens

C07K 4/10 ・from plants

C07K 4/12 ・from animals; from humans

C07K 5/00 Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof

C07K 5/02 ・containing at least one abnormal peptide link

C07K 5/0202 ・・{containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids}

C07K 5/0205 ・・{containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof}

C07K 5/0207 ・・{containing the structure -NH-(X)4-C(=0), e.g. `isosters`, replacing two amino acids}

C07K 5/021 ・・{containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K 5/06 to C07K 5/10, according to the moiety having normal peptide bonds}

C07K 5/0212 ・・{containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides}

C07K 5/0215 ・・{containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu}

C07K 5/0217 ・・{containing the structure -C(=O)-C-N-C(=O)-N-C-C(=O)-}

C07K 5/022 ・・{containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2}

C07K 5/0222 ・・・{with the first amino acid being heterocyclic, e.g. Pro, Trp}

C07K 5/0225 ・・{containing the structure -N-C-C(=O)-N-C(=O)-C-N-}

C07K 5/0227 ・・{containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K 5/06 to C07K 5/10}

C07K 5/04 ・containing only normal peptide links

C07K 5/06 ・・Dipeptides

C07K 5/06008 ・・・{with the first amino acid being neutral}

C07K 5/06017 ・・・・{and aliphatic}

C07K 5/06026 ・・・・・{the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala}

C07K 5/06034 ・・・・・{the side chain containing 2 to 4 carbon atoms}

C07K 5/06043 ・・・・・・{Leu-amino acid}

C07K 5/06052 ・・・・・・{Val-amino acid}

C07K 5/0606 ・・・・・{the side chain containing heteroatoms not provided for by C07K 5/06086 to C07K 5/06139, e.g. Ser, Met, Cys, Thr}

C07K 5/06069 ・・・・・・{Ser-amino acid}

C07K 5/06078 ・・・・{and aromatic or cycloaliphatic}

C07K 5/06086 ・・・{with the first amino acid being basic}

C07K 5/06095 ・・・・{Arg-amino acid}

C07K 5/06104 ・・・{with the first amino acid being acidic}

C07K 5/06113 ・・・・{Asp- or Asn-amino acid}

C07K 5/06121 ・・・・・{the second amino acid being aromatic or cycloaliphatic}

C07K 5/0613 ・・・・・・{Aspartame}

C07K 5/06139 ・・・{with the first amino acid being heterocyclic}

C07K 5/06147 ・・・・{and His-amino acid; Derivatives thereof}

C07K 5/06156 ・・・・{and Trp-amino acid; Derivatives thereof }

C07K 5/06165 ・・・・{and Pro-amino acid; Derivatives thereof}

C07K 5/06173 ・・・・{and Glp-amino acid; Derivatives thereof}

C07K 5/06182 ・・・・{and Pristinamycin II; Derivatives thereof}

C07K 5/06191 ・・・{containing heteroatoms different from O, S, or N }

C07K 5/08 ・・Tripeptides

C07K 5/0802 ・・・{with the first amino acid being neutral}

C07K 5/0804 ・・・・{and aliphatic}

C07K 5/0806 ・・・・・{the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala}

C07K 5/0808 ・・・・・{the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu}

C07K 5/081 ・・・・・{the side chain containing O or S as heteroatoms, e.g. Cys, Ser}

C07K 5/0812 ・・・・{and aromatic or cycloaliphatic}

C07K 5/0815 ・・・{with the first amino acid being basic}

C07K 5/0817 ・・・・{the first amino acid being Arg}

C07K 5/0819 ・・・{with the first amino acid being acidic}

C07K 5/0821 ・・・{with the first amino acid being heterocyclic, e.g. His, Pro, Trp}

C07K 5/0823 ・・・・{and Pro-amino acid; Derivatives thereof}

C07K 5/0825 ・・・・{and Glp-amino acid; Derivatives thereof}

C07K 5/0827 ・・・{containing heteroatoms different from O, S, or N }

C07K 5/10 ・・Tetrapeptides

C07K 5/1002 ・・・{with the first amino acid being neutral}

C07K 5/1005 ・・・・{and aliphatic}

C07K 5/1008 ・・・・・{the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala}

C07K 5/101 ・・・・・{the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu}

C07K 5/1013 ・・・・・{the side chain containing O or S as heteroatoms, e.g. Cys, Ser}

C07K 5/1016 ・・・・{and aromatic or cycloaliphatic}

C07K 5/1019 ・・・{with the first amino acid being basic}

C07K 5/1021 ・・・{with the first amino acid being acidic}

C07K 5/1024 ・・・{with the first amino acid being heterocyclic}

C07K 5/1027 ・・・{containing heteroatoms different from O, S, or N }

C07K 5/12 ・・Cyclic peptides {with only normal peptide bonds in the ring}

C07K 5/123 ・・・{Tripeptides}

C07K 5/126 ・・・{Tetrapeptides}

C07K 7/00 Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

C07K 7/02 ・Linear peptides containing at least one abnormal peptide link

C07K 7/04 ・Linear peptides containing only normal peptide links

C07K 7/06 ・・having 5 to 11 amino acids

C07K 7/062 ・・・{Serum thymic factor}

C07K 7/065 ・・・{Thymic humoral factor}

C07K 7/067 ・・・{Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys}

C07K 7/08 ・・having 12 to 20 amino acids (gastrins C07K 14/595; somatostatins C07K 14/655; melanotropins C07K 14/68)

C07K 7/083 ・・・{Neurotensin}

C07K 7/086 ・・・{Bombesin; Related peptides (having more than 20 amino acids C07K 14/57572)}

C07K 7/14 ・・Angiotensins: Related peptides

C07K 7/16 ・・Oxytocins; Vasopressins; Related peptides

C07K 7/18 ・・Kallidins; Bradykinins; Related peptides

C07K 7/22 ・・{Tachykinins, e.g.} Eledoisins, {Substance P}; Related peptides

C07K 7/23 ・・Luteinising hormone-releasing hormone (LHRH); Related peptides

C07K 7/28 ・・Gramicidins A, B, D; Related peptides

C07K 7/50 ・Cyclic peptides containing at least one abnormal peptide link

C07K 7/52 ・・with only normal peptide links in the ring

C07K 7/54 ・・with at least one abnormal peptide link in the ring

C07K 7/56 ・・・the cyclisation not occuring through 2,4-diamino-butanoic acid

C07K 7/58 ・・・・Bacitracins; Related peptides

C07K 7/60 ・・・the cyclisation occuring through the 4-amino group of 2,4-diamino-butanoic acid

C07K 7/62 ・・・・Polymyxins; Related peptides

C07K 7/64 ・Cyclic peptides containing only normal peptide links

C07K 7/645 ・・{Cyclosporins; Related peptides}

C07K 7/66 ・・Gramicidins S, C; Tyrocidins A,B,C; Related peptides

C07K 9/00 Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof

C07K 9/001 ・{the peptide sequence having less than 12 amino acids and not being part of a ring structure}

C07K 9/003 ・・{Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin}

C07K 9/005 ・・{containing within the molecule the substructure with m,n > 0 and m+n > 0, A,B,D,E being heteroatoms; X being a bondor a chain, e.g. muramylpeptides}

C07K 9/006 ・{the peptide sequence being part of a ring structure}

C07K 9/008 ・・{directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin}

C07K 11/00 Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof

C07K 11/02 ・cyclic, e.g. valinomycins {Derivatives thereof}

C07K 14/00 Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

C07K 14/001 ・{by chemical synthesis}

C07K 14/003 ・・{Peptide-nucleic acids (PNAs)}

C07K 14/005 ・from viruses

C07K 14/01 ・・DNA viruses

C07K 14/015 ・・・Parvoviridae, e.g. feline panleukopenia virus, human parvovirus

C07K 14/02 ・・・Hepadnaviridae, e.g. hepatitis B virus

C07K 14/025 ・・・Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus

C07K 14/03 ・・・Herpetoviridae, e.g. pseudorabies virus

C07K 14/032 ・・・・{Pseudorabies virus, i.e. Anjetzky virus}

C07K 14/035 ・・・・Herpes simplex virus I or II

C07K 14/04 ・・・・Varicella-zoster virus

C07K 14/045 ・・・・・Cytomegalovirus

C07K 14/05 ・・・・Epstein-Barr virus

C07K 14/055 ・・・・Marek`s disease virus

C07K 14/06 ・・・・Infectious bovine rhinotracheitis virus

C07K 14/065 ・・・Poxviridae, e.g. avipoxvirus

C07K 14/07 ・・・・Vaccinia virus; Variola virus

C07K 14/075 ・・・Adenoviridae

C07K 14/08 ・・RNA viruses

C07K 14/082 ・・・{Arteriviridae, e.g. EAV, PRRSV}

C07K 14/085 ・・・Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus

C07K 14/09 ・・・・Foot-and-mouth disease virus

C07K 14/095 ・・・・Rhinovirus

C07K 14/10 ・・・・Hepatitis A virus

C07K 14/105 ・・・・Poliovirus

C07K 14/11 ・・・Orthomyxoviridae, e.g. influenza virus

C07K 14/115 ・・・Paramyxoviridae, e.g. parainfluenza virus

C07K 14/12 ・・・・Mumps virus; Measles virus

C07K 14/125 ・・・・Newcastle disease virus

C07K 14/13 ・・・・Canine distemper virus

C07K 14/135 ・・・・Respiratory syncytial virus

C07K 14/14 ・・・Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus

C07K 14/145 ・・・Rhabdoviridae, e.g. rabies virus, Duvenhage virus, Mokda virus, vesicular stomatitis virus

C07K 14/15 ・・・Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus

C07K 14/155 ・・・・Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV

C07K 14/16 ・・・・・HIV-1; {HIV-2}

C07K 14/161 ・・・・・・{gag-pol, e.g. p55, p24/25, p17/18, p7, p6, p66/68, p51/52, p31/34, p32, p40}

C07K 14/162 ・・・・・・{env, e.g. gp160, gp110/120, gp41, V3, peptid T, CD4-Binding site}

C07K 14/163 ・・・・・・{Regulatory proteins, e.g. tat, nef, rev, vif, vpu, vpr, vpt, vpx}

C07K 14/165 ・・・Coronaviridae, e.g. avian infectious bronchitis virus

C07K 14/17 ・・・・Porcine transmissible gastroenteritis virus

C07K 14/175 ・・・Bunyaviridae, e.g. California encephalitis virus, Rift valley fever virus, Hantaan virus

C07K 14/18 ・・・Togaviridae; {Flaviviridae}

C07K 14/1808 ・・・・{Alphaviruses or Group A arboviruses, e.g. sindbis, VEE, EEE, WEE, semliki forest virus (rubella virus C07K 14/19)}

C07K 14/1816 ・・・・{Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus), border disease virus}

C07K 14/1825 ・・・・・{Flaviviruses or Group B arboviruses, e.g. yellow fever virus, japanese encephalitis, tick-borne encephalitis, dengue}

C07K 14/1833 ・・・・・{Hepatitis C; Hepatitis NANB}

C07K 14/1841 ・・・・・{Hepatitis G; Hepatitis NANBNCNDNE}

C07K 14/19 ・・・・Rubella virus

C07K 14/195 ・from bacteria

C07K 14/20 ・・from Spirochaetales (O), e.g. Treponema, Leptospira

C07K 14/205 ・・from Campylobacter (G)

C07K 14/21 ・・from Pseudomonadaceae (F)

C07K 14/212 ・・・{Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter}

C07K 14/215 ・・from Halobacteriaceae (F)

C07K 14/22 ・・from Neisseriaceae (F)

C07K 14/225 ・・from Alcaligenes (G)

C07K 14/23 ・・from Brucella (G)

C07K 14/235 ・・from Bordetella (G)

C07K 14/24 ・・from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia

C07K 14/245 ・・・Escherichia (G)

C07K 14/25 ・・・Shigella (G)

C07K 14/255 ・・・Salmonella (G)

C07K 14/26 ・・・Klebsiella (G)

C07K 14/265 ・・・Enterobacter (G)

C07K 14/27 ・・・Erwinia (G)

C07K 14/275 ・・・Hafnia (G)

C07K 14/28 ・・from Vibrionaceae (F)

C07K 14/285 ・・from Pasteurellaceae (F), e.g. Haemophilus influenza

C07K 14/29 ・・from Richettsiales (o)

C07K 14/295 ・・from Chlamydiales (o)

C07K 14/30 ・・from Mycoplasmatales, e.g. Pleuropneumonia-like organisms (PPLO)

C07K 14/305 ・・from Micrococcaceae (F)

C07K 14/31 ・・・from Staphylococcus (G)

C07K 14/315 ・・from Streptococcus (G), e.g. Enterococci

C07K 14/3153 ・・・{Streptokinase}

C07K 14/3156 ・・・{from Streptococcus pneumoniae (Pneumococcus) (Streptokinase C07K 14/3153)}

C07K 14/32 ・・from Bacillus (G)

C07K 14/325 ・・・Bacillus thuringiensis crystal protein (delta-endotoxin)

C07K 14/33 ・・from Clostridium (G)

C07K 14/335 ・・from Lactobacillus (G)

C07K 14/34 ・・from Corynebacterium (G)

C07K 14/345 ・・from Brevibacterium (G)

C07K 14/35 ・・from Mycobacteriaceae (F)

C07K 14/355 ・・from Nocardia (G)

C07K 14/36 ・・from Actinomyces; from Streptomyces (G)

C07K 14/365 ・・from Actinoplanes (G)

C07K 14/37 ・from fungi

C07K 14/375 ・・from Basidiomycetes

C07K 14/38 ・・from Aspergillus

C07K 14/385 ・・from Penicillium

C07K 14/39 ・・from yeasts

C07K 14/395 ・・・from Saccharomyces

C07K 14/40 ・・・from Candida

C07K 14/405 ・from algae

C07K 14/41 ・from lichens

C07K 14/415 ・from plants

C07K 14/42 ・・Lectins, e.g. concanavalin, phytohaemagglutinin

C07K 14/425 ・・Zeins

C07K 14/43 ・・{Sweetening agents, e.g.} thaumatin, {monellin}

C07K 14/435 ・from animals; from humans

C07K 14/43504 ・・{from invertebrates}

C07K 14/43509 ・・・{from crustaceans}

C07K 14/43513 ・・・{from arachnidae}

C07K 14/43518 ・・・・{from spiders}

C07K 14/43522 ・・・・{from scorpions}

C07K 14/43527 ・・・・{from ticks}

C07K 14/43531 ・・・・{from mites}

C07K 14/43536 ・・・{from worms}

C07K 14/4354 ・・・・{from nematodes}

C07K 14/43545 ・・・・・{from Caenorhabditis}

C07K 14/4355 ・・・・{from cestodes}

C07K 14/43554 ・・・・・{from Taenia}

C07K 14/43559 ・・・・{from trematodes}

C07K 14/43563 ・・・{from insects}

C07K 14/43568 ・・・・{from wasps}

C07K 14/43572 ・・・・{from bees}

C07K 14/43577 ・・・・{from flies}

C07K 14/43581 ・・・・・{from Drosophila}

C07K 14/43586 ・・・・{from silkworms}

C07K 14/4359 ・・・・{from fleas}

C07K 14/43595 ・・・{from coelenteratae, e.g. medusae}

C07K 14/44 ・・from protozoa

C07K 14/445 ・・・Plasmodium

C07K 14/45 ・・・Toxoplasma

C07K 14/455 ・・・Eimeria

C07K 14/46 ・・from vertebrates

C07K 14/461 ・・・{from fish}

C07K 14/463 ・・・{from amphibians}

C07K 14/465 ・・・from birds

C07K 14/47 ・・・from mammals

C07K 14/4701 ・・・・{not used}

C07K 14/4702 ・・・・・{Regulators; Modulating activity}

C07K 14/4703 ・・・・・・{Inhibitors; Supressors}

C07K 14/4705 ・・・・・・{stimulating, promoting or activating activity}

C07K 14/4706 ・・・・・・・{Guanosine triphosphatase activating protein, GAP}

C07K 14/4707 ・・・・・{Muscular dystrophy}

C07K 14/4708 ・・・・・・{Duchenne dystrophy}

C07K 14/471 ・・・・・・{Myotonic dystrophy}

C07K 14/4711 ・・・・・{Alzheimer`s disease; Amyloid plaque core protein}

C07K 14/4712 ・・・・・{Cystic fibrosis}

C07K 14/4713 ・・・・・{Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens}

C07K 14/4715 ・・・・・{Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein}

C07K 14/4716 ・・・・・{Muscle proteins, e.g. myosin, actin}

C07K 14/4717 ・・・・・{Plasma globulins, lactoglobulin}

C07K 14/4718 ・・・・・{Cytokine-induced proteins}

C07K 14/472 ・・・・・{Complement proteins, e.g. anaphylatoxin, C3a, C5a}

C07K 14/4721 ・・・・・{Lipocortins}

C07K 14/4722 ・・・・・{G-proteins}

C07K 14/4723 ・・・・・{Cationic antimicrobial peptides, e.g. defensins}

C07K 14/4725 ・・・・・{Proteoglycans, e.g. aggreccan}

C07K 14/4726 ・・・・・{Lectins}

C07K 14/4727 ・・・・・{Mucins, e.g. human intestinal mucin}

C07K 14/4728 ・・・・・{Calcium binding proteins, e.g. calmodulin}

C07K 14/473 ・・・・・{alpha-Glycoproteins}

C07K 14/4731 ・・・・・{Recognins, e.g. malignin}

C07K 14/4732 ・・・・・{Casein (in foodstuffs A23J)}

C07K 14/4733 ・・・・・{Acute pancreatitis-associated protein}

C07K 14/4735 ・・・・・{Villin}

C07K 14/4736 ・・・・・{Retinoblastoma protein}

C07K 14/4737 ・・・・・{C-reactive protein}

C07K 14/4738 ・・・・・{Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR (cell cycle dependent kinases C12N 9/12B1)}

C07K 14/474 ・・・・・{Pancreatic thread protein; Reg protein}

C07K 14/4741 ・・・・・{Keratin; Cytokeratin}

C07K 14/4742 ・・・・・{Bactericidal/Permeability-increasing protein (BPI)}

C07K 14/4743 ・・・・・{Insulin-like growth factor binding protein}

C07K 14/4745 ・・・・・{Cancer-associated SCM-recognition factor, CRISPP}

C07K 14/4746 ・・・・・{p53}

C07K 14/4747 ・・・・・{Apoptosis related proteins}

C07K 14/4748 ・・・・・{Tumour specific antigens; Tumour rejection antigen precursors (TRAP), e.g. MAGE}

C07K 14/475 ・・Growth factors; Growth regulators

C07K 14/4753 ・・・{Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II}

C07K 14/4756 ・・・{Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor}

C07K 14/48 ・・・Nerve growth factor (NGF)

C07K 14/485 ・・・Epidermal growth factor (EGF) (urogastrone)

C07K 14/49 ・・・Platelet-derived growth factor (PDGF)

C07K 14/495 ・・・Transforming growth factor (TGF)

C07K 14/50 ・・・Fibroblast growth factors (FGF)

C07K 14/501 ・・・・{acidic FGF (aFGF)}

C07K 14/503 ・・・・{basic FGF (bFGF)}

C07K 14/505 ・・・Erythropoietin (EPO)

C07K 14/51 ・・・Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor

C07K 14/515 ・・・Angiogenesic factors; Angiogenin

C07K 14/52 ・・Cytokines; Lymphokines; Interferons

C07K 14/521 ・・・{Chemokines}

C07K 14/522 ・・・・{Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC}

C07K 14/523 ・・・・{Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2}

C07K 14/524 ・・・{Thrombopoietin, i.e. C-MPL ligand}

C07K 14/525 ・・・Tumor necrosis factor (TNF)

C07K 14/5255 ・・・・{Lymphotoxin (LT)}

C07K 14/53 ・・・Colony-stimulating factor (CSF)

C07K 14/535 ・・・・Granulocyte CSF; Granulocyte-macrophage CSF

C07K 14/54 ・・・Interleukins (IL)

C07K 14/5403 ・・・・{IL-3}

C07K 14/5406 ・・・・{IL-4}

C07K 14/5409 ・・・・{IL-5}

C07K 14/5412 ・・・・{IL-6}

C07K 14/5415 ・・・・{Leukaemia inhibitory factor (LIF)}

C07K 14/5418 ・・・・{IL-7}

C07K 14/5421 ・・・・{IL-8}

C07K 14/5425 ・・・・{IL-9}

C07K 14/5428 ・・・・{IL-10}

C07K 14/5431 ・・・・{IL-11}

C07K 14/5434 ・・・・{IL-12}

C07K 14/5437 ・・・・{IL-13}

C07K 14/544 ・・・・{IL-14}

C07K 14/5443 ・・・・{IL-15}

C07K 14/5446 ・・・・{IL-16}

C07K 14/545 ・・・・IL-1

C07K 14/55 ・・・・IL-2

C07K 14/555 ・・・Interferons (IFN)

C07K 14/56 ・・・・IFN-alpha

C07K 14/565 ・・・・IFN-beta

C07K 14/57 ・・・・IFN-gamma

C07K 14/575 ・・Hormones (derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin C07K 14/665, e.g. corticotropin C07K 14/695)

C07K 14/57509 ・・・{Corticotropin releasing factor (CRF) (Urotensin)}

C07K 14/57518 ・・・{Placental lactogen; Chorionic somatomammotropin}

C07K 14/57527 ・・・{Calcitonin gene related peptide}

C07K 14/57536 ・・・{Endothelin, vasoactive intestinal contractor (VIC)}

C07K 14/57545 ・・・{Neuropeptide Y}

C07K 14/57554 ・・・{Prolactin}

C07K 14/57563 ・・・{Vasoactive intestinal peptide (VIP); Related peptides}

C07K 14/57572 ・・・{Gastrin releasing peptide (bombesin C07K 7/086)}

C07K 14/57581 ・・・{Thymosin; Related peptides}

C07K 14/5759 ・・・{Products of obesity genes, e.g. leptin, obese (OB), tub, fat}

C07K 14/58 ・・・Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide (ANP); Cardionatrin; Cardiodilatin

C07K 14/582 ・・・・{at least 1 amino acid in D-form}

C07K 14/585 ・・・Calcitonins

C07K 14/5855 ・・・・{at least 1 amino acid in D-form}

C07K 14/59 ・・・Follicle-stimulating hormone (FSH); Chorionic gonadotropins, e.g. HCG; Luteinising hormone (LH); Thyroid-stimulating hormone (TSH)

C07K 14/592 ・・・・{at least 1 amino acid in D-form}

C07K 14/595 ・・・Gastrins; Cholecystokinins (CCK)

C07K 14/5955 ・・・・{at least 1 amino acid in D-form}

C07K 14/60 ・・・Growth-hormone releasing factors (GH-RF) (Somatoliberin)

C07K 14/605 ・・・Glucagons

C07K 14/61 ・・・Growth hormones (GH) (Somatotropin)

C07K 14/615 ・・・・Extraction from natural sources

C07K 14/62 ・・・Insulins

C07K 14/622 ・・・・{at least 1 amino acid in D-form}

C07K 14/625 ・・・・extraction from natural sources

C07K 14/63 ・・・Motilins

C07K 14/635 ・・・Parathyroid hormone (parathormone); Parathyroid hormone-related peptides

C07K 14/64 ・・・Relaxins

C07K 14/645 ・・・Secretins

C07K 14/65 ・・・Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2

C07K 14/655 ・・・Somatostatins

C07K 14/6555 ・・・・{at least 1 amino acid in D-form}

C07K 14/66 ・・・Thymopoietins

C07K 14/662 ・・・・{at least 1 amino acid in D-form}

C07K 14/665 ・・derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin

C07K 14/67 ・・・Lipotropins, e.g. beta, gamma lipotropin

C07K 14/672 ・・・・{with at least 1 amino acid in D-form}

C07K 14/675 ・・・beta-Endorphins

C07K 14/6755 ・・・・{with at least 1 amino acid in D-form}

C07K 14/68 ・・・Melanocyte-stimulating hormone (MSH)

C07K 14/685 ・・・・alpha-Melanotropin

C07K 14/69 ・・・・beta-Melanotropin

C07K 14/695 ・・・Corticotropin (ACTH)

C07K 14/6955 ・・・・{with at least 1 amino acid in D-form}

C07K 14/70 ・・・Enkephalins

C07K 14/702 ・・・・{with at least 1 amino acid in D-form}

C07K 14/705 ・・Receptors; Cell surface antigens; Cell surface determinants {(tumour specific antigens C07K 14/4748)}

C07K 14/70503 ・・・{Immunoglobulin superfamily}

C07K 14/70507 ・・・・{CD2}

C07K 14/7051 ・・・・{T-cell receptor (TcR)-CD3 complex}

C07K 14/70514 ・・・・{CD4}

C07K 14/70517 ・・・・{CD8}

C07K 14/70521 ・・・・{CD28, CD152}

C07K 14/70525 ・・・・{ICAM molecules, e.g. CD50, CD54, CD102}

C07K 14/70528 ・・・・{CD58}

C07K 14/70532 ・・・・{B7 molecules, e.g. CD80, CD86}

C07K 14/70535 ・・・・{Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)}

C07K 14/70539 ・・・・{MHC-molecules, e.g. HLA-molecules}

C07K 14/70542 ・・・・{CD106}

C07K 14/70546 ・・・{Integrin superfamily}

C07K 14/7055 ・・・・{Integrin beta1-subunit-containing molecules, e.g. CD29, CD49}

C07K 14/70553 ・・・・{Integrin beta2-subunit-containing molecules, e.g. CD11, CD18}

C07K 14/70557 ・・・・{Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61}

C07K 14/7056 ・・・{Lectin superfamily, e.g. CD23, CD72}

C07K 14/70564 ・・・・{Selectins, e.g. CD62}

C07K 14/70567 ・・・{Nuclear receptors, e.g. retinoic acid receptor (RAR), RXR, nuclear orphan receptors}

C07K 14/70571 ・・・{for neuromediators, e.g. serotonin receptor, dopamine receptor}

C07K 14/70575 ・・・{NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154 (NGF C07K 14/48, TNF C07K 14/525)}

C07K 14/70578 ・・・{NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95 (NGF-receptor C07K 14/71, TNF-receptor C07K 14/7151)}

C07K 14/70582 ・・・{CD71}

C07K 14/70585 ・・・{CD44}

C07K 14/70589 ・・・{CD45}

C07K 14/70592 ・・・{CD52}

C07K 14/70596 ・・・{Molecules with a "CD"-designation not provided for elsewhere}

C07K 14/71 ・・・for growth factors; for growth regulators

C07K 14/715 ・・・for cytokines; for lymphokines; for interferons

C07K 14/7151 ・・・・{for tumor necrosis factor (TNF), for lymphotoxin (LT)}

C07K 14/7153 ・・・・{for colony-stimulating factors (CSF)}

C07K 14/7155 ・・・・{for interleukins (IL)}

C07K 14/7156 ・・・・{for interferons (IFN)}

C07K 14/7158 ・・・・{for chemokines}

C07K 14/72 ・・・for hormones {(for neuromediators C07K 14/70571)}

C07K 14/721 ・・・・{Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor}

C07K 14/723 ・・・・{G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor}

C07K 14/745 ・・Blood coagulation or fibrinolysis factors

C07K 14/7455 ・・・{Thrombomodulin}

C07K 14/75 ・・・Fibrinogen

C07K 14/755 ・・・Factors VIII, {e.g. factor VIII C (AHF), factor VIII Ag (VWF)}

C07K 14/76 ・・Albumins

C07K 14/765 ・・・Serum albumin, e.g. HSA

C07K 14/77 ・・・Ovalbumin

C07K 14/775 ・・Apolipopeptides

C07K 14/78 ・・Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin (CIG)

C07K 14/785 ・・Alveolar surfactant peptides; Pulmonary surfactant peptides

C07K 14/79 ・・Transferrins, e.g. lactoferrins, ovotransferrins

C07K 14/795 ・Porphyrin- or corrin-ring-containing peptides

C07K 14/80 ・・Cytochromes

C07K 14/805 ・・Haemoglobins; Myoglobins

C07K 14/81 ・Protease inhibitors

C07K 14/8103 ・・{Exopeptidase (E.C. 3.4.11-19) inhibitors}

C07K 14/8107 ・・{Endopeptidase (E.C. 3.4.21-99) inhibitors}

C07K 14/811 ・・・{Serine protease (E.C. 3.4.21) inhibitors}

C07K 14/8114 ・・・・{Kunitz type inhibitors}

C07K 14/8117 ・・・・・{Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)}

C07K 14/8121 ・・・・{Serpins}

C07K 14/8125 ・・・・・{Alpha-1-antitrypsin}

C07K 14/8128 ・・・・・{Antithrombin III}

C07K 14/8132 ・・・・・{Plasminogen activator inhibitors}

C07K 14/8135 ・・・・{Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid}

C07K 14/8139 ・・・{Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin}

C07K 14/8142 ・・・{Aspartate protease (E.C. 3.4.23) inhibitors, e.g. HIV protease inhibitors}

C07K 14/8146 ・・・{Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP}

C07K 14/815 ・・from leeches, e.g. hirudin, eglin

C07K 14/82 ・Translation products from oncogenes

C07K 14/825 ・Metallothioneins

C07K 16/00 Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies {(antibodies with enzymatic activity, e.g. abzymes C12N 9/0002)}

C07K 16/005 ・{constructed by phage libraries}

C07K 16/02 ・from eggs

C07K 16/04 ・from milk

C07K 16/06 ・from serum

C07K 16/065 ・・{Purification, fragmentation}

C07K 16/08 ・against material from viruses

C07K 16/081 ・・{from DNA viruses}

C07K 16/082 ・・・{Hepadnaviridae, e.g. hepatitis B virus}

C07K 16/084 ・・・{Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus}

C07K 16/085 ・・・{Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus}

C07K 16/087 ・・・・{Herpes simplex virus}

C07K 16/088 ・・・・{Varicella-zoster virus, e.g. cytomegalovirus}

C07K 16/10 ・・from RNA viruses, {e.g. hepatitis E virus}

C07K 16/1009 ・・・{Picornaviridae, e.g. hepatitis A virus}

C07K 16/1018 ・・・{Orthomyxoviridae, e.g. influenza virus}

C07K 16/1027 ・・・{Paramyxoviridae, e.g. respiratory syncytial virus}

C07K 16/1036 ・・・{Retroviridae, e.g. leukemia viruses}

C07K 16/1045 ・・・・{Lentiviridae, e.g. HIV, FIV, SIV}

C07K 16/1054 ・・・・・{gag-pol, e.g. p17, p24}

C07K 16/1063 ・・・・・{env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site}

C07K 16/1072 ・・・・・{Regulatory proteins, e.g. tat, rev, vpt}

C07K 16/1081 ・・・{Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus}

C07K 16/109 ・・・・{Hepatitis C virus; Hepatitis G virus}

C07K 16/12 ・against material from bacteria

C07K 16/1203 ・・{from Gram-negative bacteria}

C07K 16/1207 ・・・{from Spirochaetales (O), e.g. Treponema, Leptospira}

C07K 16/121 ・・・{from Helicobacter (Campylobacter) (G)}

C07K 16/1214 ・・・{from Pseudomonadaceae (F)}

C07K 16/1217 ・・・{from Neisseriaceae (F), e.g. Acinetobacter}

C07K 16/1221 ・・・{from Brucella (G)}

C07K 16/1225 ・・・{from Bordetella (G)}

C07K 16/1228 ・・・{from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia}

C07K 16/1232 ・・・・{from Escherichia (G)}

C07K 16/1235 ・・・・{from Salmonella (G)}

C07K 16/1239 ・・・{from Vibrionaceae (G)}

C07K 16/1242 ・・・{from Pasteurellaceae (F), e.g. Haemophilus influenza}

C07K 16/1246 ・・・{from Rickettsiales (O)}

C07K 16/125 ・・・{from Chlamydiales (O)}

C07K 16/1253 ・・・{from Mycoplasmatales, e.g. Pleuropneumonia-like organisms (PPLO)}

C07K 16/1257 ・・・{from Bacteridaceae (F)}

C07K 16/126 ・・・{from Legionella (G)}

C07K 16/1264 ・・・{from Rhizobiaceae (F)}

C07K 16/1267 ・・{from Gram-positive bacteria}

C07K 16/1271 ・・・{from Micrococcaceae (F), e.g. Staphylococcus}

C07K 16/1275 ・・・{from Streptococcus (G)}

C07K 16/1278 ・・・{from Bacillus (G)}

C07K 16/1282 ・・・{from Clostridium (G)}

C07K 16/1285 ・・・{from Corynebacterium (G)}

C07K 16/1289 ・・・{from Mycobacteriaceae (F)}

C07K 16/1292 ・・・{from Actinomyces; from Streptomyces (G)}

C07K 16/1296 ・・・{from Listeria}

C07K 16/14 ・against material from fungi, algea or lichens

C07K 16/16 ・against material from plants

C07K 16/18 ・against material from animals or humans

C07K 16/20 ・・from protozoa

C07K 16/205 ・・・{Plasmodium}

C07K 16/22 ・・against growth factors; {against growth regulators}

C07K 16/24 ・・against cytokines, lymphokines or interferons

C07K 16/241 ・・・{Tumor Necrosis Factors}

C07K 16/242 ・・・・{Lymphotoxin (LT)}

C07K 16/243 ・・・{Colony Stimulating Factors}

C07K 16/244 ・・・{Interleukins (IL)}

C07K 16/245 ・・・・{IL-1}

C07K 16/246 ・・・・{IL-2}

C07K 16/247 ・・・・{IL-4}

C07K 16/248 ・・・・{IL-6}

C07K 16/249 ・・・{Interferons}

C07K 16/26 ・・against hormones; {against hormone releasing or inhibiting factors}

C07K 16/28 ・・against receptors, cell surface antigens or cell surface determinants

C07K 16/2803 ・・・{against the immunoglobulin superfamily}

C07K 16/2806 ・・・・{against CD2}

C07K 16/2809 ・・・・[N. against the T-cell receptor (TcR)-CD3 complex]

C07K 16/2812 ・・・・{against CD4}

C07K 16/2815 ・・・・{against CD8}

C07K 16/2818 ・・・・{against CD28 or CD152}

C07K 16/2821 ・・・・{against ICAM molecules, e.g. CD50, CD54, CD102}

C07K 16/2824 ・・・・{against CD58}

C07K 16/2827 ・・・・{against B7 molecules, e.g. CD80, CD86}

C07K 16/283 ・・・・{against Fc-receptors, e.g. CD16, CD32, CD64 (CD23 C07K 16/2851)}

C07K 16/2833 ・・・・{against MHC-molecules, e.g. HLA-molecules}

C07K 16/2836 ・・・・{against CD106}

C07K 16/2839 ・・・{against the integrin superfamily}

C07K 16/2842 ・・・・{against integrin beta1-subunit-containing molecules, e.g. CD29, CD49}

C07K 16/2845 ・・・・{against integrin beta2-subunit-containing molecules, e.g. CD11, CD18}

C07K 16/2848 ・・・・{against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61}

C07K 16/2851 ・・・{against the lectin superfamily, e.g. CD23, CD72}

C07K 16/2854 ・・・・{against selectins, e.g. CD62}

C07K 16/2857 ・・・{against nuclear receptors, e.g. retinoic acid receptor (RAR), RXR, orphan receptor}

C07K 16/286 ・・・{against neuromediator receptors, e.g. serotonin receptor, dopamine receptor}

C07K 16/2863 ・・・{against receptors for growth factors, growth regulators}

C07K 16/2866 ・・・{against receptors for cytokines, lymphokines, interferons}

C07K 16/2869 ・・・{against hormone receptors (for antibodies against neuromediator receptors C07K 16/286)}

C07K 16/2872 ・・・{against prion molecules, e.g. CD230}

C07K 16/2875 ・・・{against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154 (against

C07K 16/2878 ・・・{against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95}

C07K 16/2881 ・・・{against CD71}

C07K 16/2884 ・・・{against CD44}

C07K 16/2887 ・・・{against CD20}

C07K 16/289 ・・・{against CD45}

C07K 16/2893 ・・・{against CD52}

C07K 16/2896 ・・・{against molecules with a "CD"-designation, not provided for elsewhere}

C07K 16/30 ・・・from tumour cells

C07K 16/3007 ・・・・{Carcino-embryonic Antigens}

C07K 16/3015 ・・・・{Breast}

C07K 16/3023 ・・・・{Lung}

C07K 16/303 ・・・・{Liver or Pancreas}

C07K 16/3038 ・・・・{Kidney, bladder}

C07K 16/3046 ・・・・{Stomach, Intestines}

C07K 16/3053 ・・・・{Skin, nerves, brain}

C07K 16/3061 ・・・・{Blood cells}

C07K 16/3069 ・・・・{Reproductive system, e.g. ovaria, uterus, testes, prostate}

C07K 16/3076 ・・・・{against structure-related tumour-associated moieties}

C07K 16/3084 ・・・・・{against tumour-associated gangliosides}

C07K 16/3092 ・・・・・{against tumour-associated mucins}

C07K 16/32 ・・against translation products of oncogenes

C07K 16/34 ・・against blood group antigens

C07K 16/36 ・・against blood coagulation factors

C07K 16/38 ・against protease inhibitors of peptide structure

C07K 16/40 ・against enzymes

C07K 16/42 ・against immunoglobulins

C07K 16/4208 ・・{against an idiotypic determinant on Ig}

C07K 16/4216 ・・・{against anti-viral Ig}

C07K 16/4225 ・・・・{against anti-HIV Ig}

C07K 16/4233 ・・・{against anti-bacterial Ig}

C07K 16/4241 ・・・{against anti-human or anti-animal Ig}

C07K 16/425 ・・・・{against anti-protozoal Ig}

C07K 16/4258 ・・・・{against anti-receptor Ig}

C07K 16/4266 ・・・・・{against anti-tumor receptor Ig}

C07K 16/4275 ・・・・・{against anti-CD4 Ig}

C07K 16/4283 ・・{against an allotypic or isotypic determinant on Ig}

C07K 16/4291 ・・・{against IgE}

C07K 16/44 ・against material not provided for elsewhere, {e.g. haptens, metals, DNA, RNA, amino acids}

C07K 16/46 ・Hybrid immunoglobulins (hybrids of an immunoglobulin with a peptide not being an immunoglobulin C07K 19/00)

C07K 16/461 ・・{Igs containing Ig-regions, -domains or -residues form different species}

C07K 16/462 ・・・{Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another}

C07K 16/464 ・・・{Igs containing CDR-residues from one specie grafted between FR-residues from another}

C07K 16/465 ・・・・{with additional modified FR-residues}

C07K 16/467 ・・・{Igs with modifications in the FR-residues only}

C07K 16/468 ・・{Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies}

C07K 17/00 Carrier-bound or immobilised peptides (carrier-bound or immobilised enzymes C12N 11/00); Preparation thereof

C07K 17/02 ・Peptides being immobilised on, or in, an organic carrier

C07K 17/04 ・・entrapped within the carrier, e.g. gel, hollow fibre

C07K 17/06 ・・attached to the carrier via a bridging agent

C07K 17/08 ・・the carrier being a synthetic polymer

C07K 17/10 ・・the carrier being a carbohydrate

C07K 17/12 ・・・Cellulose or derivatives thereof

C07K 17/14 ・Peptides being immobilised on, or in, an inorganic carrier

C07K 19/00 Hybrid peptides

C07K 2299/00 Coordinates from 3D structures of peptides, e.g. proteins or enzymes

C07K 2316/00 Immunoglobulins specific feautures

C07K 2316/50 ・Immunoglobulins characterised by their fragments

C07K 2316/52 ・・Constant or Fc region

C07K 2316/95 ・Antibodies with agonistic, e.g. apoptotic, activity upon their specific binding to an antigen

C07K 2316/96 ・Antibodies with antagonisticactivity upon their specific binding to an antigen

C07K 2317/00 Immunoglobulins specific feautures

C07K 2317/10 ・characterized by their source of isolation or production

C07K 2317/11 ・・isolated from eggs

C07K 2317/12 ・・isolated from milk

C07K 2317/13 ・・isolated from plants

C07K 2317/14 ・・Specific host cells or culture conditions, e.g. components, pH or temperature

C07K 2317/20 ・characterized by taxonomic origin

C07K 2317/21 ・・from primates, e.g. man

C07K 2317/22 ・・from camelids, e.g. camel, llama or dromedary

C07K 2317/23 ・・from birds

C07K 2317/24 ・・containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

C07K 2317/30 ・characterized by aspects of specificity or valency

C07K 2317/31 ・・multispecific

C07K 2317/32 ・・specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor

C07K 2317/33 ・・Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity

C07K 2317/34 ・・Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

C07K 2317/35 ・・Valency

C07K 2317/40 ・characterized by post-translational modification

C07K 2317/41 ・・Glycosylation, sialylation, or fucosylation

C07K 2317/50 ・characterized by immunoglobulin fragments

C07K 2317/51 ・・Complete heavy chain or Fd fragment, i.e. VH + CH1

C07K 2317/515 ・・Complete light chain, i.e. VL + CL

C07K 2317/52 ・・Constant or Fc region; Isotype

C07K 2317/522 ・・・CH1 domain

C07K 2317/524 ・・・CH2 domain

C07K 2317/526 ・・・CH3 domain

C07K 2317/528 ・・・CH4 domain

C07K 2317/53 ・・・Hinge

C07K 2317/54 ・・F(ab')2

C07K 2317/55 ・・Fab or Fab'

C07K 2317/56 ・・variable (Fv) region , i.e. VH and/or VL

C07K 2317/565 ・・・Complementarity determining region (CDR)

C07K 2317/567 ・・・Framework region (FR)

C07K 2317/569 ・・・Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobodyR

C07K 2317/60 ・characterized by non-natural combinations of immunoglobulin fragments

C07K 2317/62 ・・comprising only variable region components

C07K 2317/622 ・・・Single chain antibody (scFv)

C07K 2317/624 ・・・Disulfide-stabilized antibody (dsFv)

C07K 2317/626 ・・・Diabody or triabody

C07K 2317/64 ・・comprising a combination of variable region and constant region components

C07K 2317/66 ・・comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1

C07K 2317/70 ・characterized by effect upon binding to a cell or to an antigen

C07K 2317/71 ・・Decreased effector function due to an Fc-modification

C07K 2317/72 ・・Increased effector function due to an Fc-modification

C07K 2317/73 ・・Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

C07K 2317/732 ・・・Antibody-dependent cellular cytotoxicity (ADCC)

C07K 2317/734 ・・・Complement-dependent cytotoxicity (CDC)

C07K 2317/74 ・・Inducing cell proliferation

C07K 2317/75 ・・Agonist effect on antigen

C07K 2317/76 ・・Antagonist effect on antigen, e.g. neutralization or inhibition of binding

C07K 2317/77 ・・Internalization into the cell

C07K 2317/80 ・remaining in the (producing) cell, i.e. intracellular antibodies or intrabodies

C07K 2317/81 ・・functional in the endoplasmatic reticulum (ER) or the Golgi apparatus

C07K 2317/82 ・・functional in the cytoplasm, the inner aspect of the cell membrane, the nucleus or the mitochondria

C07K 2317/90 ・characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

C07K 2317/92 ・・Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

C07K 2317/94 ・・Stability, e.g. half-life, pH, temperature or enzyme-resistance

C07K 2318/00 Antibody mimetics or scaffolds

C07K 2318/10 ・Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes

C07K 2318/20 ・Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics

C07K 2319/00 Fusion polypeptide

C07K 2319/003 ・containing an enzyme part without its signal sequence

C07K 2319/006 ・・containing an enzyme signal sequence possibly accompanied by part or the whole of the mature enzyme

C07K 2319/01 ・containing a localisation/targetting motif

C07K 2319/02 ・・containing a signal sequence

C07K 2319/03 ・・containing a transmembrane segment

C07K 2319/033 ・・containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif

C07K 2319/034 ・・containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved

C07K 2319/035 ・・containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

C07K 2319/036 ・・targeting to the medium outside of the cell, e.g. type III secretion

C07K 2319/04 ・・containing an ER retention signal such as a C-terminal HDEL motif

C07K 2319/05 ・・containing a GOLGI retention signal

C07K 2319/055 ・・containing a signal for localisation to secretory granules (for exocytosis)

C07K 2319/06 ・・containing a lysosomal/endosomal localisation signal

C07K 2319/07 ・・containing a mitochondrial localisation signal

C07K 2319/08 ・・containing a chloroplats localisation signal

C07K 2319/09 ・・containing a nuclear localisation signal

C07K 2319/095 ・・containing a nuclear export signal

C07K 2319/10 ・・containing a tag for extracellular membrane crossing, e.g. TAT or VP22

C07K 2319/20 ・containing a tag with affinity for a non-protein ligand

C07K 2319/21 ・・containing a His-tag

C07K 2319/22 ・・containing a Strep-tag

C07K 2319/23 ・・containing a GST-tag

C07K 2319/24 ・・containing a MBP(maltose binding protein)-tag

C07K 2319/30 ・Non-immunoglobulin-derived peptide or protein having an imunoglobulin constant or Fc region, or a fragment thereof, attached thereto

C07K 2319/31 ・fusions, other than Fc, for prolonged plasma life, e.g. albumin

C07K 2319/32 ・fusions with soluble part of a cell surface receptor, "decoy receptors"

C07K 2319/33 ・fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

C07K 2319/35 ・containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin

C07K 2319/40 ・containing a tag for immunodetection, or an epitope for immunisation

C07K 2319/41 ・・containing a Myc-tag

C07K 2319/42 ・・containing a HA(hemagglutinin)-tag

C07K 2319/43 ・・containing a FLAG-tag

C07K 2319/50 ・containing protease site

C07K 2319/55 ・containing a fusion with a toxin, e.g. diphteria toxin

C07K 2319/60 ・containing spectroscopic/fluorescent detection, e.g. green fluorescent protein (GFP)

C07K 2319/61 ・containing an enzyme fusion for detection (lacZ, luciferase)

C07K 2319/70 ・containing domain for protein-protein interaction

C07K 2319/705 ・・containing a protein-A fusion

C07K 2319/71 ・・containing domain for transcriptional activaation, e.g. VP16

C07K 2319/715 ・・・containing a domain for ligand dependent transcriptional activation, e.g. containing a steroid receptor domain

C07K 2319/72 ・・containing SH2 domain

C07K 2319/73 ・・containing coiled-coiled motif (leucine zippers)

C07K 2319/735 ・・containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)

C07K 2319/74 ・・containing a fusion for binding to a cell surface receptor

C07K 2319/75 ・・・containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

C07K 2319/80 ・containing a DNA binding domain, e.g. Lacl or Tet-repressor

C07K 2319/81 ・・containing a Zn-finger domain for DNA binding

C07K 2319/85 ・containing an RNA binding domain

C07K 2319/90 ・containing a motif for post-translational modification

C07K 2319/91 ・・containing a motif for glycosylation

C07K 2319/912 ・・・containing a GPI (phosphatidyl-inositol glycane) anchor

C07K 2319/915 ・・containing a motif for acylation

C07K 2319/92 ・・containing an intein ("protein splicing") domain

C07K 2319/95 ・containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)